1. PRCA and Immunogenecity (Background)
   • PRCA and Immunogenecity
   
   
2. PRCA Patient Database Update
   • Patient Database Update
   • Dear Doctor: Important Update - Eprex (epoetin alfa) - Pure Red Cell Aplasia (PRCA, Erythroblastopenia)
   
   
3. CURRENT LITERATURE ON PRCA
   • European Best Practice Guidelines 9-13 Anaema Management
   • The haematopoietic effect of recombinant human erythropoietin in haemodialysis is independent of the mode of administration ( i.v. or s.c. )
   • Human Response to Recombinant Human Proteins
   
   
4. Further Information
   • Further Information for Customers and Patients

  Human Response to Recombinant Human Proteins

"The scientific literature suggests that all exogenous proteins have the potential to elicit an immune response, particularly when administered via the subcutaneous (SC) route."

Seth Porter
Human Response to Recombinant Human Proteins
Journal of Pharmaceutical Sciences, vol. 90, No.1, January 2001